From a VtES perspective, or at least if you’re interested in the whole vampire/werewolf/.. theme, it’s interesting to note, that the next Magic: the Gathering expansion named Innistrad has a very strong horror angle. The expansion is subtitled “Horror Lurks Within” and the product information reads as following:
“Innistrad is a plane of menace and dread where every creature hides a darker aspect. Here, hedonistic vampires stalk the shadows to quench their thirst, and the full moon can transform a simple villager into a savage werewolf. Best to huddle inside, Planeswalker, lest the horrors of this world rend you limb from limb.“
- White — Angels/Clerics
- Blue — Ghosts/Mutants/Zombies
- Black — Vampires/Zombies/Demons
- Red — Vampires/Werewolves
- Green — Werewolves/Shamans
One of the most interesting aspects of the new expansion are the so-called double-faced cards (although the practical handling in the game is a nightmare). These double-faced cards are cards with two faces (two side with card text), but no regular MtG card back. The card is put into play with one specific side up, but this can change depending on certain conditions (if a creature died this turn, the number of spells being played, etc.) I think this gives the whole horror theme a nice twist in terms of the game mechanic.
Reference: Innistrad product page.
Post Scriptum: Yes, I am a little envious of the money WotC is able to spend on the artwork for the Magic cards (in contrast to most VtES cards).